Game crashing in Windows 10. I have dgVoodoo.

I have a piece of string, how long is it?

First win10 is not on the supported OS list. Have you done the various basic things, you can find in any of the seemingly endless "my game don't work, fix it" threads such as:

https://www.gog.com/forum/general/problems_with_starting_uprising_join_or_die

May want to head over to the forums concerning your game located here:

https://www.gog.com/forum/blood_series

I see at least 2 threads about crashing under windows 10 on the front page.