OK - bear in mind that my ability threshold is lower than most. I normally resort to cheats before giving up but couldn't progress even with assistance:

- Psychonauts. Too hard for me to control.

- Tomb Raider 2. I normally died, restarted from the previous checkpoint and eventually progressed. However, the number of times I had to restart an area increased beyond my patience

- Prince of Persia Warrior Within. The save points were just outside my reach. When I retried, I'd have to replay quite a large section only to fail miserably...again.

I never run out of talent.