If you're having an awful time trying to get NWN to work on win10 with 1920x1080 as your resolution then I would suggest Right clicking -> Properties -> Compatibility -> click Run in 640x480 Screen Resolution -> run as administrator -> run compatibility mode for win xp service pack 3.

The game opens up in your native resolution but makes your desktop 640x480. Might make alt tabbing a pain, but at least the game works.