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For me, it is:

-Disable storybook videos and intro mod
-Skip cutscenes autohotkey (makes CTRL behave like turbo spacebar)
-Debug Console Enabler (for experimentation)
-autoapply oils
-autogathering mod for herbs only

Now if only there was a way to disable the white messages that appear at the bottom left when I pick a herb or fight an enemy I don't have oil for.
I'm running goty 1.31 version
I use AutoLoot
Increased creature loot
Indestructible items
Over 9000-Weight limit mod
More money for traders