I swear to you this could've been the new Metroid franchise. It had exploration, grappling hooks, a female protagonist who looked cool. What made it stand out a lot to me when I played were 3 particular things. One was it was done in isometric which is not seen as much outside of Zelda style games and ARPG games usually so a futuristic place with guns and space level tech is pretty interesting or at least it was very different when I first discovered this game. The second feature was an infection counter that made exploration on a time limit so you had to keep track of decontamination rooms to save and restore your infection counter. If it got to 100% you died by turning into an enemy monster basically which is, again, not such a common thing with a lot of games especially exploration games back then. One of my favorites was the third where depending on which weapon you used then it had different effects. Use the fire weapon on a biological enemy and you smoke them easy but another enemy type would have no special reaction and still take a few shots and the third enemy type would get faster, stronger, and generally meaner. You had to choose carefully what weapon you used on an enemy on the fly via a ring menu. It is a mechanic I have almost never seen outside of something like Clive Barker's Undying where you could effectively only hurt enemies with specific weapons to them or Soul Reaver 1 when you had to destroy evolved vampires through specific means such as sunlight pockets or water. This one feels like it was ahead of its time but also if it were not for one or two game breaking bugs such as a worm boss becoming unkillable even when you reload due to a bug or something in the code then this really could've been the future I think.