Xorbius: Same happened to me. X-fi gamer card. Played fine and then went to load and all sound except voices play now. I also had another glitch where it wouldn't let me save for like an hour, I just kept playing hoping it would fix but it didn't and once I went out of town, I got in a battle and I couldn't even draw any weapons no matter what I tried, so I died and since I couldn't save and it didn't auto-save, I lost over an hour of play time.
That second bug is literally the very same thing that I experienced myself, right after talking to Loredo at his house (I lost an hour of play time because of that). And now, I find myself with that first bug, no voices or ambient sounds at all! I tried loading a bunch of previous saves, but same issue, they're all without any sound...
I didn't see anything about it in the changelog, but I really hope the upcoming patch will solve those two issues.