Brasas: Bottom line - this stuff cannot be calculated even assuming perfect information and computation power.
Well yes, that's the point. However, some macro observations can be made, and it's all the more valuable because there are seriously
people who'd argue against it on first principles.
For example, I'm a big fan of a certain sport. Said sport allows men and women to participate, but there's no women's league. It's heavily strength- and endurance-based, and men have a yooge advantage. So arguments can be made (and probably have been and are being made) that there should be a less physically demanding women's league, so more women would be able to enjoy the sport and win and feel all warm and fuzzy. Then again, arguments can me made that a separate-but-equal league would be treated as second-rate, not worthy of attention, fewer women would participate and the amount of fuzzy feelings would actually decrease. I'm in the first camp (and not just because I won the national championship in 2015 on a fluke), and I would respectfully disagree with a member of the other camp. But both of us will agree that those who think that women shouldn't be allowed to ride bikes at all are dead wrong and also major assholes.
Brasas: Is that what you consider being a radical skeptic?
No, I mean the hypocrites and genuinely crazy people who think all knowledge is unreliable
and therefore completely worthless. Meanwhile, most of them keep relying on [unreliable] knowledge in their daily life. In this case it'd be something like "how can we know when people are happy, what if Putin orders you to say you're happy or he'll shoot you?", "what if people are happier when they're suffering?", etc.